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The number needed to treat in patients at low risk to prevent one premature death was 250 for one and one-half years, and 24 patients at arachionic acid high risk to prevent one death. (7) The U.S. Physicians' Health Study (8) surveyed roughly 20,000 male physicians and found no apparent association between fish consumption arachionic acid or supplementation with omega-3 fatty acids and risk for myocardial infarction, nonsudden cardiac death, or total cardiovascular mortality. However, men who consumed fish at least once per week had a 50 percent reduction in the risk for sudden death and arachionic acid a significant reduction in all-cause mortality. (8) A reanalysis (9) of the U.S. Physicians' Health Study found a significant inverse relationship between blood levels of omega-3 fatty acids and the risk of sudden death in men with no history of CHD.
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