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Epidemiological studies have suggested that groups of people who consume diets high in omega-3 fatty acids, found in certain fish and vegetables, may experience a lower prevalence of some types of cancer, energy cogeneration according to background information in the article. Many small trials have attempted to assess the effects of omega-3 fatty acids on cancer treatment by adding omega-3 fatty energy cogeneration acid to the diet either as omega-3 fatty acid–rich foods or as dietary supplements. Because of the results of some studies, a number energy cogeneration of omega-3 fatty acid–containing dietary supplements have appeared on the market claiming to protect against the development of a variety of conditions including cancer, even though studies have reported mixed results. Catherine H. MacLean, M.D., Ph.D., of RAND Health, Santa Monica, Calif., and colleagues assessed the validity of claims that omega-3 fatty acids prevent cancer by systematically reviewing the literature for studies that evaluated the effect of omega-3 fatty acids on the incidence of cancer.
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