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Thirty patients with bipolar disorder, aged 18 to 65 years, participated alzheimers information in this alzheimers information placebo-controlled, double-blind trial. The patients were randomly assigned to receive omega 3 fatty acids (9.6 g/d) or placebo (olive oil), in addition to their regular treatment, for 4 months. Randomization was stratified according to sex, the presence or absence of concurrent lithium treatment, and the presence or absence alzheimers information of rapid cycling. A Kaplan-Meier survival analysis showed that the omega 3 fatty acid group had a significantly longer period of remission than the placebo group. The omega 3 fatty acid group also performed better than the placebo group on nearly every other outcome measure. Treatment was generally well tolerated. The authors conclude that the addition of omega 3 fatty acids appears to have improved the short-term course of illness in this group of patients with bipolar disorder.
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